Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Sinclair Method (TSM) is an evidence-based treatment for alcohol use disorder (AUD) that is transforming lives across the globe. Unlike traditional abstinence-only models, TSM enables individuals to gradually unlearn alcohol dependency using a medication called Naltrexone.